What it is
Selank is a synthetic peptide developed in Russia, based on tuftsin, a fragment of an immune protein, with extra amino acids added for stability. It is usually given as a nasal spray.
How it is thought to work
Research suggests effects on GABA signalling (the same calming system targeted by benzodiazepines, but without the same sedation in studies), on serotonin and on BDNF, a brain growth factor. These mechanisms come mostly from animal and laboratory work.
The evidence
- Clinical studies come mainly from Russia. They are small, often not blinded to modern standards and mostly published in Russian.
- There are no large, independent, placebo-controlled trials meeting current international standards.
- Claims about focus, memory and immunity are largely extrapolated from animal data.
Regulatory status
Selank is registered in Russia as a nasal preparation. It is not approved by the US FDA, the European Medicines Agency or Kenya's Pharmacy and Poisons Board.
Safety
Short-term use in the published studies has been reported as well tolerated, but long-term safety data are absent. Interactions with antidepressants, anxiety medicines and alcohol are not well characterised.
Our view
Persistent anxiety deserves a proper assessment. Proven treatments, including talking therapies, sleep repair and, where needed, established medicines, come first. If what you describe sounds like an anxiety disorder or depression, the doctor will say so and help you get the right support.
Talk it through with a doctor
Whether any of these medicines is right for you depends on your health, your history and your goals. The first phone consultation is free, and there is no obligation.
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